Dynamic Visibility

View model

using System.Collections.ObjectModel;
using CommunityToolkit.Mvvm.ComponentModel;
using CommunityToolkit.Mvvm.Input;
using LiveChartsCore;
using LiveChartsCore.SkiaSharpView;

namespace ViewModelsSamples.General.Visibility;

public partial class ViewModel : ObservableObject
{
    public ISeries[] Series { get; set; } =
    {
        new ColumnSeries<double>
        {
            Values = new ObservableCollection<double> { 2, 5, 4, 3 },
            IsVisible = true
        },
        new ColumnSeries<double>
        {
            Values = new ObservableCollection<double> { 6, 3, 2, 8 },
            IsVisible = true
        },
        new ColumnSeries<double>
        {
            Values = new ObservableCollection<double> { 4, 2, 8, 7 },
            IsVisible = true
        }
    };

    [RelayCommand]
    public void ToggleSeries0()
    {
        Series[0].IsVisible = !Series[0].IsVisible;
    }

    [RelayCommand]
    public void ToggleSeries1()
    {
        Series[1].IsVisible = !Series[1].IsVisible;
    }

    [RelayCommand]
    public void ToggleSeries2()
    {
        Series[2].IsVisible = !Series[2].IsVisible;
    }
}

Form code behind

using System.Windows.Forms;
using LiveChartsCore.SkiaSharpView.WinForms;
using ViewModelsSamples.General.Visibility;

namespace WinFormsSample.General.Visibility;

public partial class View : UserControl
{
    private readonly CartesianChart cartesianChart;

    public View()
    {
        InitializeComponent();
        Size = new System.Drawing.Size(100, 100);

        var viewModel = new ViewModel();

        cartesianChart = new CartesianChart
        {
            Series = viewModel.Series,

            // out of livecharts properties...
            Location = new System.Drawing.Point(0, 50),
            Size = new System.Drawing.Size(100, 50),
            Anchor = AnchorStyles.Left | AnchorStyles.Right | AnchorStyles.Top | AnchorStyles.Bottom
        };

        Controls.Add(cartesianChart);

        var b1 = new Button { Text = "toggle 1", Location = new System.Drawing.Point(0, 0) };
        b1.Click += (object sender, System.EventArgs e) => viewModel.ToggleSeries0();
        Controls.Add(b1);

        var b2 = new Button { Text = "toggle 2", Location = new System.Drawing.Point(80, 0) };
        b2.Click += (object sender, System.EventArgs e) => viewModel.ToggleSeries1();
        Controls.Add(b2);

        var b3 = new Button { Text = "toggle 3", Location = new System.Drawing.Point(160, 0) };
        b3.Click += (object sender, System.EventArgs e) => viewModel.ToggleSeries2();
        Controls.Add(b3);
    }
}

Articles you might also find useful: